early cellular replicative senescence_Brca1<tm2.1Thl>/Brca1<tm2.1Thl>

http://metadb.riken.jp/0008008I129C57BL6Brca1tm21ThlBrca1tm21ThlBrca1tm21Thl

early cellular replicative senescence_Brca1<tm2.1Thl>/Brca1<tm2.1Thl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm2.1Thl>/Brca1<tm2.1Thl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Brca1<tm2.1Thl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• Reena. Shakya, et.al., BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity., Science (New York, N.Y.), 2011, 334
  http://rdf.ncbi.nlm.nih.gov/pubmed/22034435