early cellular replicative senescence_Mtf2<tm1.1Hko>/Mtf2<tm1.1Hko>,Phc2<tm1Hko>/Phc2<tm1Hko>

http://metadb.riken.jp/0008008I129S1Sv129X1SvJC57BL6Mtf2tm11HkoMtf2tm11HkoPhc2tm1HkoPhc2tm1HkoPhc2tm1HkoMtf2tm11Hko

early cellular replicative senescence_Mtf2<tm1.1Hko>/Mtf2<tm1.1Hko>,Phc2<tm1Hko>/Phc2<tm1Hko>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polyhomeotic-like 2 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1860454
• metal response element binding transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:105050

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mtf2<tm1.1Hko>/Mtf2<tm1.1Hko>,Phc2<tm1Hko>/Phc2<tm1Hko>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Phc2<tm1Hko>|Mtf2<tm1.1Hko>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• Xiangzhi. Li, et.al., Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes., Molecular and cellular biology, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21059868