early cellular replicative senescence_Brca2<tm1Hst>/Brca2<tm2Hst>

http://metadb.riken.jp/0008008I129S7SvEvBrdC57BL6Brca2tm1HstBrca2tm2HstBrca2tm2HstBrca2tm1Hst

early cellular replicative senescence_Brca2<tm1Hst>/Brca2<tm2Hst>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 2, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:109337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca2<tm1Hst>/Brca2<tm2Hst>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Brca2<tm2Hst>|Brca2<tm1Hst>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• Greg. Donoho, et.al., Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice., Genes, chromosomes & cancer, 2003, 36
  http://rdf.ncbi.nlm.nih.gov/pubmed/12619154