increased lung tumor incidence_Del(15Krt80-Krt18)1Tmm/+,Tg(Actb-KRAS*G12V,-luc)#Lche/0

http://metadb.riken.jp/0008014I129S7SvEvBrdC57BL6FVBNDel15Krt80Krt181TmmTgActbKRASG12VlucLche0Del15Krt80Krt181TmmTgActbKRASG12VlucLche

increased lung tumor incidence_Del(15Krt80-Krt18)1Tmm/+,Tg(Actb-KRAS*G12V,-luc)#Lche/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Lukas C Heukamp
  http://metadb.riken.jp/db/mgi_rdf/MGI:5526089
• deletion, Chr 15, Thomas M Magin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:4410572

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Del(15Krt80-Krt18)1Tmm/+,Tg(Actb-KRAS*G12V,-luc)#Lche/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• +|Del(15Krt80-Krt18)1Tmm|Tg(Actb-KRAS*G12V,-luc)#Lche

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung tumor incidence
  http://purl.obolibrary.org/obo/MP_0008014

文献

http://purl.org/net/cito/citesAsAuthority

• Katharina. König, et.al., Loss of the keratin cytoskeleton is not sufficient to induce epithelial mesenchymal transition in a novel KRAS driven sporadic lung cancer mouse model., PloS one, 2013, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/23536778