increased liver tumor incidence_Bhmt<tm1.2Zei>/Bhmt<tm1.2Zei>

http://metadb.riken.jp/0008019I129P2OlaHsdC57BL6Bhmttm12ZeiBhmttm12ZeiBhmttm12Zei

increased liver tumor incidence_Bhmt<tm1.2Zei>/Bhmt<tm1.2Zei>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• betaine-homocysteine methyltransferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1339972

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bhmt<tm1.2Zei>/Bhmt<tm1.2Zei>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bhmt<tm1.2Zei>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver tumor incidence
  http://purl.obolibrary.org/obo/MP_0008019

文献

http://purl.org/net/cito/citesAsAuthority

• Ya-Wen. Teng, et.al., Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21878621