increased liver tumor incidence_Stk11<tm1Mmt>/Stk11<+>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0008019I129S7SvEvBrd129X1SvJStk11tm1MmtStk11Trp53tm1BrdTrp53tm1BrdStk11Trp53tm1BrdStk11tm1Mmt

increased liver tumor incidence_Stk11<tm1Mmt>/Stk11<+>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• serine/threonine kinase 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341870

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stk11<tm1Mmt>/Stk11<+>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stk11<+>|Trp53<tm1Brd>|Stk11<tm1Mmt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver tumor incidence
  http://purl.obolibrary.org/obo/MP_0008019

文献

http://purl.org/net/cito/citesAsAuthority

• H. Takeda, et.al., Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/-p53-/- compound mutant mice., Oncogene, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16278673