abnormal T cell morphology_Zap70<tm2.1Mmal>/Zap70<tm2.1Mmal>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

http://metadb.riken.jp/0008037I129P2OlaHsdBALBcJC57BL6JDBA2JZap70tm21MmalZap70tm21MmalTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboZap70tm21Mmal

abnormal T cell morphology_Zap70<tm2.1Mmal>/Zap70<tm2.1Mmal>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• zeta-chain (TCR) associated protein kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99613
• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Zap70<tm2.1Mmal>/Zap70<tm2.1Mmal>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)71Vbo|Zap70<tm2.1Mmal>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/cJ * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell morphology
  http://purl.obolibrary.org/obo/MP_0008037

文献

http://purl.org/net/cito/citesAsAuthority

• A. Magnan, et.al., T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase., The Journal of experimental medicine, 2001, 194
  http://rdf.ncbi.nlm.nih.gov/pubmed/11514605