decreased NK T cell number_Pdpk1<tm1Mlw>/Pdpk1<tm1.1Daca>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008040I129P2OlaHsdBALBcC57BL6DBA2Pdpk1tm1MlwPdpk1tm11DacaTgCd4cre1Cwi0TgCd4cre1CwiPdpk1tm11DacaPdpk1tm1Mlw

decreased NK T cell number_Pdpk1<tm1Mlw>/Pdpk1<tm1.1Daca>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• 3-phosphoinositide dependent protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338068
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdpk1<tm1Mlw>/Pdpk1<tm1.1Daca>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Pdpk1<tm1.1Daca>|Pdpk1<tm1Mlw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/c * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased NK T cell number
  http://purl.obolibrary.org/obo/MP_0008040

文献

http://purl.org/net/cito/citesAsAuthority

• David K. Finlay, et.al., Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20944007