abnormal NK T cell physiology_Sh2d1a<tm1.1Knic>/Sh2d1a<tm1.1Knic>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Tg(UBC-cre/ERT2)1Ejb/0

http://metadb.riken.jp/0008042I129SSvEv129X1SvJC57BL6Sh2d1atm11KnicSh2d1atm11KnicGtROSA26Sortm1EYFPCosGtROSA26SorTgUBCcreERT21Ejb0GtROSA26Sortm1EYFPCosTgUBCcreERT21EjbSh2d1atm11KnicGtROSA26Sor

abnormal NK T cell physiology_Sh2d1a<tm1.1Knic>/Sh2d1a<tm1.1Knic>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Tg(UBC-cre/ERT2)1Ejb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH2 domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328352
• transgene insertion 1, Eric J Brown
  http://metadb.riken.jp/db/mgi_rdf/MGI:3707330
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2d1a<tm1.1Knic>/Sh2d1a<tm1.1Knic>,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Tg(UBC-cre/ERT2)1Ejb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(EYFP)Cos>|Tg(UBC-cre/ERT2)1Ejb|Sh2d1a<tm1.1Knic>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal NK T cell physiology
  http://purl.obolibrary.org/obo/MP_0008042

文献

http://purl.org/net/cito/citesAsAuthority

• Rupali. Das, et.al., The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation., Blood, 2013, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/23430111