increased NK cell number_Sphk1<tm1.1Cgh>/Sphk1<tm2Cgh>,Sphk2<tm1.1Cgh>/Sphk2<tm1.1Cgh>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008044I129S4SvJaeC57BL6CBASphk1tm11CghSphk1tm2CghSphk2tm11CghSphk2tm11CghTgMx1cre1Cgn0Sphk2tm11CghTgMx1cre1CgnSphk1tm2CghSphk1tm11Cgh

increased NK cell number_Sphk1<tm1.1Cgh>/Sphk1<tm2Cgh>,Sphk2<tm1.1Cgh>/Sphk2<tm1.1Cgh>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sphingosine kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861380
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• sphingosine kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1316649

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sphk1<tm1.1Cgh>/Sphk1<tm2Cgh>,Sphk2<tm1.1Cgh>/Sphk2<tm1.1Cgh>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sphk2<tm1.1Cgh>|Tg(Mx1-cre)1Cgn|Sphk1<tm2Cgh>|Sphk1<tm1.1Cgh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased NK cell number
  http://purl.obolibrary.org/obo/MP_0008044

文献

http://purl.org/net/cito/citesAsAuthority

• Craig N. Jenne, et.al., T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19808259