decreased NK cell number_Il15<tm1Imx>/Il15<tm1Imx>

http://metadb.riken.jp/0008045IC57BL6Il15tm1ImxIl15tm1ImxIl15tm1Imx

decreased NK cell number_Il15<tm1Imx>/Il15<tm1Imx>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 15
  http://metadb.riken.jp/db/mgi_rdf/MGI:103014

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il15<tm1Imx>/Il15<tm1Imx>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il15<tm1Imx>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased NK cell number
  http://purl.obolibrary.org/obo/MP_0008045

文献

http://purl.org/net/cito/citesAsAuthority

• M K. Kennedy, et.al., Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice., The Journal of experimental medicine, 2000, 191
  http://rdf.ncbi.nlm.nih.gov/pubmed/10704459
• Teresa. Bianchi, et.al., c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis., Blood, 2006, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/16449532
• Naoko. Satoh-Takayama, et.al., Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense., Immunity, 2008, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19084435