increased memory T cell number_Cd4<tm1(cre/ERT2)Thbu>/Cd4<+>,Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>

http://metadb.riken.jp/0008049I129S1Sv129X1SvJC57BL6Cd4tm1creERT2ThbuCd4Tgfbr2tm1KarlTgfbr2tm1KarlTgfbr2tm1KarlCd4Cd4tm1creERT2Thbu

increased memory T cell number_Cd4<tm1(cre/ERT2)Thbu>/Cd4<+>,Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD4 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88335
• transforming growth factor, beta receptor II
  http://metadb.riken.jp/db/mgi_rdf/MGI:98729

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd4<tm1(cre/ERT2)Thbu>/Cd4<+>,Tgfbr2<tm1Karl>/Tgfbr2<tm1Karl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfbr2<tm1Karl>|Cd4<+>|Cd4<tm1(cre/ERT2)Thbu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased memory T cell number
  http://purl.obolibrary.org/obo/MP_0008049

文献

http://purl.org/net/cito/citesAsAuthority

• Anna. Sledzińska, et.al., TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function., PLoS biology, 2013, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/24115907