abnormal podocyte slit junction morphology_Prkci<tm1Rfar>/Prkci<tm1Rfar>,Tg(NPHS2-cre)295Lbh/0

http://metadb.riken.jp/0008062I129P2OlaHsdC57BL6SJLPrkcitm1RfarPrkcitm1RfarTgNPHS2cre295Lbh0TgNPHS2cre295LbhPrkcitm1Rfar

abnormal podocyte slit junction morphology_Prkci<tm1Rfar>/Prkci<tm1Rfar>,Tg(NPHS2-cre)295Lbh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein kinase C, iota
  http://metadb.riken.jp/db/mgi_rdf/MGI:99260
• transgene insertion 295, Lawrence B Holzman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450360

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkci<tm1Rfar>/Prkci<tm1Rfar>,Tg(NPHS2-cre)295Lbh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(NPHS2-cre)295Lbh|Prkci<tm1Rfar>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal podocyte slit junction morphology
  http://purl.obolibrary.org/obo/MP_0008062

文献

http://purl.org/net/cito/citesAsAuthority

• Tobias B. Huber, et.al., Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome., Journal of the American Society of Nephrology : JASN, 2009, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/19279126