absent B cells_Atg3<tm1.1Ywh>/Atg3<tm1.1Ywh>,Fnip1<m1Btlr>/Fnip1<m1Btlr>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0008071I129SSvEv129S1Sv129X1SvJC57BL6JAtg3tm11YwhAtg3tm11YwhFnip1m1BtlrFnip1m1BtlrGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26Sortm1creERTNatGtROSA26SorAtg3tm11YwhFnip1m1Btlr

absent B cells_Atg3<tm1.1Ywh>/Atg3<tm1.1Ywh>,Fnip1<m1Btlr>/Fnip1<m1Btlr>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• autophagy related 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915091
• folliculin interacting protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444668
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atg3<tm1.1Ywh>/Atg3<tm1.1Ywh>,Fnip1<m1Btlr>/Fnip1<m1Btlr>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(cre/ERT)Nat>|Gt(ROSA)26Sor<+>|Atg3<tm1.1Ywh>|Fnip1<m1Btlr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent B cells
  http://purl.obolibrary.org/obo/MP_0008071

文献

http://purl.org/net/cito/citesAsAuthority

• Owen M. Siggs, et.al., Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity., Proceedings of the National Academy of Sciences of the United States of America, 2016, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/27303042