increased CD4-positive, alpha beta T cell number_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Runx1<tm1Toku>/Runx1<tm1Toku>,Runx3<tm1Itan>/Runx3<tm1Itan>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008074I129P2OlaHsd129S2SvPasC57BL6DBA2H2Ab1tm1GruH2Ab1tm1GruRunx1tm1TokuRunx1tm1TokuRunx3tm1ItanRunx3tm1ItanTgCd4cre1Cwi0Runx3tm1ItanRunx1tm1TokuH2Ab1tm1GruTgCd4cre1Cwi

increased CD4-positive, alpha beta T cell number_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Runx1<tm1Toku>/Runx1<tm1Toku>,Runx3<tm1Itan>/Runx3<tm1Itan>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histocompatibility 2, class II antigen A, beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103070
• runt related transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99852
• runt related transcription factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:102672
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Runx1<tm1Toku>/Runx1<tm1Toku>,Runx3<tm1Itan>/Runx3<tm1Itan>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Runx3<tm1Itan>|Runx1<tm1Toku>|H2-Ab1<tm1Gru>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008074

文献

http://purl.org/net/cito/citesAsAuthority

• Ruka. Setoguchi, et.al., Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development., Science (New York, N.Y.), 2008, 319
  http://rdf.ncbi.nlm.nih.gov/pubmed/18258917