increased CD4-positive, alpha beta T cell number_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcraTcrb)8Rest/0

http://metadb.riken.jp/0008074I129S1Sv129X1SvJC57BL6Ctla4tm1AllCtla4tm1AllTgTcraTcrb8Rest0Ctla4tm1AllTgTcraTcrb8Rest

increased CD4-positive, alpha beta T cell number_Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcraTcrb)8Rest/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytotoxic T-lymphocyte-associated protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88556
• transgene insertion 8, Nicholas Restifo
  http://metadb.riken.jp/db/mgi_rdf/MGI:3051149

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctla4<tm1All>/Ctla4<tm1All>,Tg(TcraTcrb)8Rest/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctla4<tm1All>|Tg(TcraTcrb)8Rest

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008074

文献

http://purl.org/net/cito/citesAsAuthority

• Luca. Gattinoni, et.al., CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent., Blood, 2006, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/16882704