decreased CD4-positive, alpha beta T cell number_Sla<tm1Weis>/Sla<tm1Weis>,Zap70<tm1Weis>/Zap70<tm1Weis>

http://metadb.riken.jp/0008075I129129X1SvJC57BL6Slatm1WeisSlatm1WeisZap70tm1WeisZap70tm1WeisZap70tm1WeisSlatm1Weis

decreased CD4-positive, alpha beta T cell number_Sla<tm1Weis>/Sla<tm1Weis>,Zap70<tm1Weis>/Zap70<tm1Weis>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• zeta-chain (TCR) associated protein kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99613
• src-like adaptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104295

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sla<tm1Weis>/Sla<tm1Weis>,Zap70<tm1Weis>/Zap70<tm1Weis>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Zap70<tm1Weis>|Sla<tm1Weis>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• T. Sosinowski, et.al., The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection., Immunity, 2001, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/11567635