decreased CD4-positive, alpha beta T cell number_Itk<tm1Ljb>/Itk<tm1Ljb>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?

http://metadb.riken.jp/0008075I129C57BL10Itktm1LjbItktm1LjbTgTcra5CC7Tcrb5CC7IWepTgTcra5CC7Tcrb5CC7IWepItktm1Ljb

decreased CD4-positive, alpha beta T cell number_Itk<tm1Ljb>/Itk<tm1Ljb>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• IL2 inducible T cell kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96621
• transgene insertion I, William E Paul
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761176

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itk<tm1Ljb>/Itk<tm1Ljb>,Tg(Tcra5CC7,Tcrb5CC7)IWep/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tcra5CC7,Tcrb5CC7)IWep|Itk<tm1Ljb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/10

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Julie A. Lucas, et.al., The absence of Itk inhibits positive selection without changing lineage commitment., Journal of immunology (Baltimore, Md. : 1950), 2002, 168
  http://rdf.ncbi.nlm.nih.gov/pubmed/12055226