decreased CD4-positive, alpha beta T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?

http://metadb.riken.jp/0008075I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgLCKprBCL236SjkBcl11btm1AvramTgLCKprBCL236SjkTgCd4cre1Cwi

decreased CD4-positive, alpha beta T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• B cell leukemia/lymphoma 11B
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929913
• transgene insertion 36, Stanley J Korsmeyer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448240

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bcl11b<tm1Avram>|Tg(LCKprBCL2)36Sjk|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Diana I. Albu, et.al., BCL11B is required for positive selection and survival of double-positive thymocytes., The Journal of experimental medicine, 2007, 204
  http://rdf.ncbi.nlm.nih.gov/pubmed/17998389