decreased CD4-positive, alpha beta T cell number_Cd8a<tm1Asin>/Cd8a<tm1Asin>,Cd8b1<tm1Litt>/Cd8b1<tm1Litt>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>

http://metadb.riken.jp/0008075I129FVBNCd8atm1AsinCd8atm1AsinCd8b1tm1LittCd8b1tm1LittH2Ab1tm1GruH2Ab1tm1GruCd8b1tm1LittCd8atm1AsinH2Ab1tm1Gru

decreased CD4-positive, alpha beta T cell number_Cd8a<tm1Asin>/Cd8a<tm1Asin>,Cd8b1<tm1Litt>/Cd8b1<tm1Litt>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD8 antigen, beta chain 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88347
• histocompatibility 2, class II antigen A, beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103070
• CD8 antigen, alpha chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:88346

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd8a<tm1Asin>/Cd8a<tm1Asin>,Cd8b1<tm1Litt>/Cd8b1<tm1Litt>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd8b1<tm1Litt>|Cd8a<tm1Asin>|H2-Ab1<tm1Gru>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Batu. Erman, et.al., Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model., Journal of immunology (Baltimore, Md. : 1950), 2006, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/17082573