decreased CD4-positive, alpha beta T cell number_Tg(Lck-cre)548Jxm/?,Upf2<tm1Btp>/Upf2<tm1Btp>

http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6CBATgLckcre548JxmUpf2tm1BtpUpf2tm1BtpUpf2tm1BtpTgLckcre548Jxm

decreased CD4-positive, alpha beta T cell number_Tg(Lck-cre)548Jxm/?,Upf2<tm1Btp>/Upf2<tm1Btp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• UPF2 regulator of nonsense transcripts homolog (yeast)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449307
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Lck-cre)548Jxm/?,Upf2<tm1Btp>/Upf2<tm1Btp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Upf2<tm1Btp>|Tg(Lck-cre)548Jxm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Joachim. Weischenfeldt, et.al., NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements., Genes & development, 2008, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/18483223