decreased CD4-positive, alpha beta T cell number_Gt(ROSA)26Sor<tm1(DTA)Lky>/Gt(ROSA)26Sor<tm1(DTA)Lky>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6DBA2GtROSA26Sortm1DTALkyGtROSA26Sortm1DTALkyTgCd4cre1Cwi0TgCd4cre1CwiGtROSA26Sortm1DTALky

decreased CD4-positive, alpha beta T cell number_Gt(ROSA)26Sor<tm1(DTA)Lky>/Gt(ROSA)26Sor<tm1(DTA)Lky>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(DTA)Lky>/Gt(ROSA)26Sor<tm1(DTA)Lky>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Gt(ROSA)26Sor<tm1(DTA)Lky>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• David. Voehringer, et.al., Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice., Journal of immunology (Baltimore, Md. : 1950), 2008, 180
  http://rdf.ncbi.nlm.nih.gov/pubmed/18354198