decreased CD4-positive, alpha beta T cell number_Dicer1<tm1Tara>/Dicer1<tm1Tara>,Foxn1<tm3(cre)Nrm>/Foxn1<+>

http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6NHsdDicer1tm1TaraDicer1tm1TaraFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDicer1tm1TaraFoxn1

decreased CD4-positive, alpha beta T cell number_Dicer1<tm1Tara>/Dicer1<tm1Tara>,Foxn1<tm3(cre)Nrm>/Foxn1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box N1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102949
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dicer1<tm1Tara>/Dicer1<tm1Tara>,Foxn1<tm3(cre)Nrm>/Foxn1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxn1<tm3(cre)Nrm>|Dicer1<tm1Tara>|Foxn1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6NHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Aikaterini S. Papadopoulou, et.al., The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor., Nature immunology, 2011, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/22179202