decreased CD4-positive, alpha beta T cell number_Tg(Ins2-TFRC/OVA)296Wehi/0,Tg(TcraTcrb)425Cbn/0

http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6TgIns2TFRCOVA296Wehi0TgTcraTcrb425Cbn0TgIns2TFRCOVA296WehiTgTcraTcrb425Cbn

decreased CD4-positive, alpha beta T cell number_Tg(Ins2-TFRC/OVA)296Wehi/0,Tg(TcraTcrb)425Cbn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 296, Walter and Eliza Hall Institute of Medical Research
  http://metadb.riken.jp/db/mgi_rdf/MGI:3578728
• transgene insertion 425, Frank Carbone
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046085

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Ins2-TFRC/OVA)296Wehi/0,Tg(TcraTcrb)425Cbn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-TFRC/OVA)296Wehi|Tg(TcraTcrb)425Cbn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Maureen A. Su, et.al., Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire., The Journal of clinical investigation, 2008, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/18414681