decreased CD4-positive, alpha beta T cell number_Cd8a<tm1Asin>/Cd8a<tm1Asin>,Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/?

http://metadb.riken.jp/0008075I129S1Sv129X1SvJC57BL10FVBNCd8atm1AsinCd8atm1AsinTgCD2TcraF5CD2TcrbF51KioTgCD2TcraF5CD2TcrbF51KioCd8atm1Asin

decreased CD4-positive, alpha beta T cell number_Cd8a<tm1Asin>/Cd8a<tm1Asin>,Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD8 antigen, alpha chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:88346
• transgene insertion 1, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:3706669

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd8a<tm1Asin>/Cd8a<tm1Asin>,Tg(CD2-TcraF5,CD2-TcrbF5)1Kio/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CD2-TcraF5,CD2-TcrbF5)1Kio|Cd8a<tm1Asin>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/10 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Batu. Erman, et.al., Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model., Journal of immunology (Baltimore, Md. : 1950), 2006, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/17082573