decreased CD4-positive, alpha beta T cell number_Becn1<tm1.1Bflu>/Becn1<tm1.1Bflu>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008075I129S1SvC57BL6DBA2Becn1tm11BfluBecn1tm11BfluTgCd4cre1Cwi0Becn1tm11BfluTgCd4cre1Cwi

decreased CD4-positive, alpha beta T cell number_Becn1<tm1.1Bflu>/Becn1<tm1.1Bflu>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• beclin 1, autophagy related
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891828

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Becn1<tm1.1Bflu>/Becn1<tm1.1Bflu>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Becn1<tm1.1Bflu>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• J R. Kovacs, et.al., Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery., Cell death and differentiation, 2012, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/21660048