decreased CD4-positive, alpha beta T cell number_Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0

http://metadb.riken.jp/0008075I129S4SvJaeC57BL6CBAICRFaddtm1WntFaddtm1WntTgFadd33Wnt0TgLckcreI57Jxm0Faddtm1WntTgLckcreI57JxmTgFadd33Wnt

decreased CD4-positive, alpha beta T cell number_Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 33, Astar Winoto
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358104
• transgene insertion I57, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177579
• Fas (TNFRSF6)-associated via death domain
  http://metadb.riken.jp/db/mgi_rdf/MGI:109324

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fadd<tm1Wnt>/Fadd<tm1Wnt>,Tg(Fadd)33Wnt/0,Tg(Lck-cre)I57Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fadd<tm1Wnt>|Tg(Lck-cre)I57Jxm|Tg(Fadd)33Wnt

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• N H. Kabra, et.al., T cell-specific FADD-deficient mice: FADD is required for early T cell development., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11353862