decreased CD4-positive, alpha beta T cell number_Itk<tm1Litt>/Itk<tm1Litt>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

http://metadb.riken.jp/0008075I129S4SvJaeC57BL6DBA2JItktm1LittItktm1LittTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboItktm1Litt

decreased CD4-positive, alpha beta T cell number_Itk<tm1Litt>/Itk<tm1Litt>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559
• IL2 inducible T cell kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96621

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itk<tm1Litt>/Itk<tm1Litt>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)71Vbo|Itk<tm1Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• X C. Liao, et.al., Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk., Immunity, 1995, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/8777721