decreased CD4-positive, alpha beta T cell number_Tg(TcrAND)53Hed/?,Themis<tm1Gasc>/Themis<tm1Gasc>

http://metadb.riken.jp/0008075I129S6SvEvTacC57BL6SJLTgTcrAND53HedThemistm1GascThemistm1GascThemistm1GascTgTcrAND53Hed

decreased CD4-positive, alpha beta T cell number_Tg(TcrAND)53Hed/?,Themis<tm1Gasc>/Themis<tm1Gasc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 53, Stephen M Hedrick
  http://metadb.riken.jp/db/mgi_rdf/MGI:3054631
• thymocyte selection associated
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443552

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(TcrAND)53Hed/?,Themis<tm1Gasc>/Themis<tm1Gasc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Themis<tm1Gasc>|Tg(TcrAND)53Hed

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Guo. Fu, et.al., Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19597499