decreased CD4-positive, alpha beta T cell number_Ptprc<tm1Mak>/Ptprc<tm1Mak>,Tg(TcraTcrb)425Cbn/0

http://metadb.riken.jp/0008075I129SvBALBcC57BL6Ptprctm1MakPtprctm1MakTgTcraTcrb425Cbn0TgTcraTcrb425CbnPtprctm1Mak

decreased CD4-positive, alpha beta T cell number_Ptprc<tm1Mak>/Ptprc<tm1Mak>,Tg(TcraTcrb)425Cbn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, receptor type, C
  http://metadb.riken.jp/db/mgi_rdf/MGI:97810
• transgene insertion 425, Frank Carbone
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046085

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptprc<tm1Mak>/Ptprc<tm1Mak>,Tg(TcraTcrb)425Cbn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraTcrb)425Cbn|Ptprc<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Julie. Zikherman, et.al., CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development., Immunity, 2010, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/20346773