decreased CD4-positive, alpha beta T cell number_H2<b>/H2<b>,Itk<tm1Ljb>/Itk<tm1Ljb>,Tg(TcrAND)53Hed/?

http://metadb.riken.jp/0008075IC3HHeJC57BL6C57BL10H2bH2bItktm1LjbItktm1LjbTgTcrAND53HedItktm1LjbH2bTgTcrAND53Hed

decreased CD4-positive, alpha beta T cell number_H2<b>/H2<b>,Itk<tm1Ljb>/Itk<tm1Ljb>,Tg(TcrAND)53Hed/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• IL2 inducible T cell kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96621
• histocompatibility-2, MHC
  http://metadb.riken.jp/db/mgi_rdf/MGI:95894
• transgene insertion 53, Stephen M Hedrick
  http://metadb.riken.jp/db/mgi_rdf/MGI:3054631

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2<b>/H2<b>,Itk<tm1Ljb>/Itk<tm1Ljb>,Tg(TcrAND)53Hed/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itk<tm1Ljb>|H2<b>|Tg(TcrAND)53Hed

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H/HeJ * C57BL/6 * C57BL/10

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Julie A. Lucas, et.al., The absence of Itk inhibits positive selection without changing lineage commitment., Journal of immunology (Baltimore, Md. : 1950), 2002, 168
  http://rdf.ncbi.nlm.nih.gov/pubmed/12055226