decreased CD4-positive, alpha beta T cell number_Pik3c3<tm1.1Flv>/Pik3c3<tm1.1Flv>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008075IC57BL6C57BL6NDBA2Pik3c3tm11FlvPik3c3tm11FlvTgCd4cre1Cwi0TgCd4cre1CwiPik3c3tm11Flv

decreased CD4-positive, alpha beta T cell number_Pik3c3<tm1.1Flv>/Pik3c3<tm1.1Flv>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol 3-kinase catalytic subunit type 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2445019
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3c3<tm1.1Flv>/Pik3c3<tm1.1Flv>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Pik3c3<tm1.1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6N * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Tim. Willinger, et.al., Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22592798