decreased CD4-positive, alpha beta T cell number_Sppl2a<m1Anu>/Sppl2a<m1Anu>,Tg(Vav-BCL2)1Jad/?

http://metadb.riken.jp/0008075IC57BL6JAnuSppl2am1AnuSppl2am1AnuTgVavBCL21JadSppl2am1AnuTgVavBCL21Jad

decreased CD4-positive, alpha beta T cell number_Sppl2a<m1Anu>/Sppl2a<m1Anu>,Tg(Vav-BCL2)1Jad/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jerry M Adams
  http://metadb.riken.jp/db/mgi_rdf/MGI:3037069
• signal peptide peptidase like 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913802

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sppl2a<m1Anu>/Sppl2a<m1Anu>,Tg(Vav-BCL2)1Jad/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sppl2a<m1Anu>|Tg(Vav-BCL2)1Jad

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6JAnu

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Hannes. Bergmann, et.al., B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A., The Journal of experimental medicine, 2013, 210
  http://rdf.ncbi.nlm.nih.gov/pubmed/23267016