abnormal CD4-positive T cell differentiation_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0008076I129C57BL6DBA2Stat3tm1DlvStat3tm1DlvTgCd4cre1CwiStat3tm1DlvTgCd4cre1Cwi

abnormal CD4-positive T cell differentiation_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat3<tm1Dlv>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal CD4-positive T cell differentiation
  http://purl.obolibrary.org/obo/MP_0008076

文献

http://purl.org/net/cito/citesAsAuthority

• Liang. Zhou, et.al., IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways., Nature immunology, 2007, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/17581537