increased CD8-positive, alpha-beta T cell number_Cd4<tm1Litt>/Cd4<tm1Litt>

http://metadb.riken.jp/0008078I129S2SvPasCd4tm1LittCd4tm1LittCd4tm1Litt

increased CD8-positive, alpha-beta T cell number_Cd4<tm1Litt>/Cd4<tm1Litt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD4 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88335

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd4<tm1Litt>/Cd4<tm1Litt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd4<tm1Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008078

文献

http://purl.org/net/cito/citesAsAuthority

• Mark M W. Chong, et.al., Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells., Genes & development, 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/20360383
• N. Killeen, et.al., Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4., The EMBO journal, 1993, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/8467804