increased CD8-positive, alpha-beta T cell number_Cdk6<tm2.1Phin>/Cdk6<tm2.1Phin>,Il2ra<tm1Dw>/Il2ra<tm1Dw>

http://metadb.riken.jp/0008078I129S4SvJaeC57BL6FVBNCdk6tm21PhinCdk6tm21PhinIl2ratm1DwIl2ratm1DwIl2ratm1DwCdk6tm21Phin

increased CD8-positive, alpha-beta T cell number_Cdk6<tm2.1Phin>/Cdk6<tm2.1Phin>,Il2ra<tm1Dw>/Il2ra<tm1Dw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 2 receptor, alpha chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:96549
• cyclin-dependent kinase 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1277162

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk6<tm2.1Phin>/Cdk6<tm2.1Phin>,Il2ra<tm1Dw>/Il2ra<tm1Dw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il2ra<tm1Dw>|Cdk6<tm2.1Phin>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008078

文献

http://purl.org/net/cito/citesAsAuthority

• Miaofen G. Hu, et.al., CDK6 kinase activity is required for thymocyte development., Blood, 2011, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/21508411