decreased CD8-positive, alpha-beta T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6DBA2Cbfbtm1ItanCbfbtm1ItanTgCd4cre1Cwi0TgCd4cre1CwiCbfbtm1Itan

decreased CD8-positive, alpha-beta T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• core binding factor beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:99851
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cbfb<tm1Itan>/Cbfb<tm1Itan>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Cbfb<tm1Itan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Mark M W. Chong, et.al., Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells., Genes & development, 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/20360383