decreased CD8-positive, alpha-beta T cell number_Runx1<tm1Toku>/Runx1<+>,Runx3<tm1Itan>/Runx3<tm1Itan>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6DBA2Runx1tm1TokuRunx1Runx3tm1ItanRunx3tm1ItanTgCd4cre1Cwi0Runx1tm1TokuTgCd4cre1CwiRunx1Runx3tm1Itan

decreased CD8-positive, alpha-beta T cell number_Runx1<tm1Toku>/Runx1<+>,Runx3<tm1Itan>/Runx3<tm1Itan>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• runt related transcription factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:102672
• runt related transcription factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99852

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Runx1<tm1Toku>/Runx1<+>,Runx3<tm1Itan>/Runx3<tm1Itan>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Runx1<tm1Toku>|Tg(Cd4-cre)1Cwi|Runx1<+>|Runx3<tm1Itan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Ruka. Setoguchi, et.al., Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development., Science (New York, N.Y.), 2008, 319
  http://rdf.ncbi.nlm.nih.gov/pubmed/18258917