decreased CD8-positive, alpha-beta T cell number_Psmb11<tm1(Psmb8)Khog>/Psmb11<tm1(Psmb8)Khog>,Psmb8<tm1Hjf>/Psmb8<tm1Hjf>

http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6Psmb11tm1Psmb8KhogPsmb11tm1Psmb8KhogPsmb8tm1HjfPsmb8tm1HjfPsmb11tm1Psmb8KhogPsmb8tm1Hjf

decreased CD8-positive, alpha-beta T cell number_Psmb11<tm1(Psmb8)Khog>/Psmb11<tm1(Psmb8)Khog>,Psmb8<tm1Hjf>/Psmb8<tm1Hjf>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346527
• proteasome (prosome, macropain) subunit, beta type, 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921152

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psmb11<tm1(Psmb8)Khog>/Psmb11<tm1(Psmb8)Khog>,Psmb8<tm1Hjf>/Psmb8<tm1Hjf>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psmb11<tm1(Psmb8)Khog>|Psmb8<tm1Hjf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Yan. Xing, et.al., Thymoproteasome subunit-β5T generates peptide-MHC complexes specialized for positive selection., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23569244