decreased CD8-positive, alpha-beta T cell number_Nkap<tm1.1Viss>/Y,Tg(Lck-cre)1Cwi/0

http://metadb.riken.jp/0008079I129S1Sv129X1SvJNkaptm11VissYTgLckcre1Cwi0TgLckcre1CwiNkaptm11Viss

decreased CD8-positive, alpha-beta T cell number_Nkap<tm1.1Viss>/Y,Tg(Lck-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448687
• NFKB activating protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914300

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nkap<tm1.1Viss>/Y,Tg(Lck-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)1Cwi|Nkap<tm1.1Viss>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Anthony G. Pajerowski, et.al., NKAP is a transcriptional repressor of notch signaling and is required for T cell development., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19409814