decreased CD8-positive, alpha-beta T cell number_Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0008079I129S4SvJae129S6SvEvTacC57BL6CBAMcl1tm1YwhMcl1tm1YwhTgLckcre548Jxm0Mcl1tm1YwhTgLckcre548Jxm

decreased CD8-positive, alpha-beta T cell number_Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• myeloid cell leukemia sequence 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101769
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mcl1<tm1Ywh>|Tg(Lck-cre)548Jxm

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Ivan. Dzhagalov, et.al., The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages., Journal of immunology (Baltimore, Md. : 1950), 2008, 181
  http://rdf.ncbi.nlm.nih.gov/pubmed/18566418