decreased CD8-positive, alpha-beta T cell number_Cd8b1<tm1Litt>/Cd8b1<tm1Litt>

http://metadb.riken.jp/0008079I129S4SvJaeC57BL6JCd8b1tm1LittCd8b1tm1LittCd8b1tm1Litt

decreased CD8-positive, alpha-beta T cell number_Cd8b1<tm1Litt>/Cd8b1<tm1Litt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD8 antigen, beta chain 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88347

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd8b1<tm1Litt>/Cd8b1<tm1Litt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd8b1<tm1Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• H Y. Irie, et.al., The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development., Journal of immunology (Baltimore, Md. : 1950), 1998, 161
  http://rdf.ncbi.nlm.nih.gov/pubmed/9647223
• M E. Crooks, et.al., Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain., Immunity, 1994, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/7889415