decreased CD8-positive, alpha-beta T cell number_Picalm<tm1.1Tmae>/Picalm<tm1.1Tmae>,Tg(Vav1-icre)A2Kio/0

http://metadb.riken.jp/0008079I129S6SvEvTacC57BL6C57BL10CBASJLPicalmtm11TmaePicalmtm11TmaeTgVav1icreA2Kio0Picalmtm11TmaeTgVav1icreA2Kio

decreased CD8-positive, alpha-beta T cell number_Picalm<tm1.1Tmae>/Picalm<tm1.1Tmae>,Tg(Vav1-icre)A2Kio/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol binding clathrin assembly protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385902
• transgene insertion A2, Dimitris Kioussis
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449945

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Picalm<tm1.1Tmae>/Picalm<tm1.1Tmae>,Tg(Vav1-icre)A2Kio/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Picalm<tm1.1Tmae>|Tg(Vav1-icre)A2Kio

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Yuichi. Ishikawa, et.al., Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology., Haematologica, 2015, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/25552701