decreased CD8-positive, alpha-beta T cell number_Tg(TcraTcrb)1100Mjb/?,Themis<tm1Gasc>/Themis<tm1Gasc>

http://metadb.riken.jp/0008079I129S6SvEvTacC57BL6TgTcraTcrb1100MjbThemistm1GascThemistm1GascThemistm1GascTgTcraTcrb1100Mjb

decreased CD8-positive, alpha-beta T cell number_Tg(TcraTcrb)1100Mjb/?,Themis<tm1Gasc>/Themis<tm1Gasc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1100, Michael J Bevan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055219
• thymocyte selection associated
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443552

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(TcraTcrb)1100Mjb/?,Themis<tm1Gasc>/Themis<tm1Gasc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Themis<tm1Gasc>|Tg(TcraTcrb)1100Mjb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Guo. Fu, et.al., Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling., Nature immunology, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19597499