decreased CD8-positive, alpha-beta T cell number_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp)a20Cwe/0

http://metadb.riken.jp/0008079I129S7SvEvBrdC57BL6Prnptm1CwePrnptm1CweTgPrnpa20Cwe0TgPrnpa20CwePrnptm1Cwe

decreased CD8-positive, alpha-beta T cell number_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp)a20Cwe/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769
• transgene insertion a20, Charles Weissmann
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652457

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp)a20Cwe/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp)a20Cwe|Prnp<tm1Cwe>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Evelyne. Jouvin-Marche, et.al., Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus., Journal of immunology (Baltimore, Md. : 1950), 2006, 176
  http://rdf.ncbi.nlm.nih.gov/pubmed/16517717