decreased CD8-positive, alpha-beta T cell number_Elk4<tm1Rtr>/Elk4<tm1Rtr>,Tg(TcrLCMV)327Sdz/?

http://metadb.riken.jp/0008079I129SvC57BL6DBA2Elk4tm1RtrElk4tm1RtrTgTcrLCMV327SdzElk4tm1RtrTgTcrLCMV327Sdz

decreased CD8-positive, alpha-beta T cell number_Elk4<tm1Rtr>/Elk4<tm1Rtr>,Tg(TcrLCMV)327Sdz/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ELK4, member of ETS oncogene family
  http://metadb.riken.jp/db/mgi_rdf/MGI:102853
• transgene insertion 327, Birgit Ledermann
  http://metadb.riken.jp/db/mgi_rdf/MGI:2665109

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Elk4<tm1Rtr>/Elk4<tm1Rtr>,Tg(TcrLCMV)327Sdz/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Elk4<tm1Rtr>|Tg(TcrLCMV)327Sdz

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Patrick S. Costello, et.al., Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection., Nature immunology, 2004, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/14770179