decreased CD8-positive, alpha-beta T cell number_Map3k3<tm1Bisu>/Map3k3<tm2Bisu>,Tg(Lck-cre)548Jxm/0

http://metadb.riken.jp/0008079IC57BL6CBAMap3k3tm1BisuMap3k3tm2BisuTgLckcre548Jxm0TgLckcre548JxmMap3k3tm2BisuMap3k3tm1Bisu

decreased CD8-positive, alpha-beta T cell number_Map3k3<tm1Bisu>/Map3k3<tm2Bisu>,Tg(Lck-cre)548Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198
• mitogen-activated protein kinase kinase kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346874

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Map3k3<tm1Bisu>/Map3k3<tm2Bisu>,Tg(Lck-cre)548Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)548Jxm|Map3k3<tm2Bisu>|Map3k3<tm1Bisu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Xiaofang. Wang, et.al., MEKK3 is essential for lymphopenia-induced T cell proliferation and survival., Journal of immunology (Baltimore, Md. : 1950), 2009, 182
  http://rdf.ncbi.nlm.nih.gov/pubmed/19265138