decreased CD8-positive, alpha-beta T cell number_Tg(Vav1-Lin28b)C3Apla/0

http://metadb.riken.jp/0008079IC57BL6TgVav1Lin28bC3Apla0TgVav1Lin28bC3Apla

decreased CD8-positive, alpha-beta T cell number_Tg(Vav1-Lin28b)C3Apla/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion C3, Peter Aplan
  http://metadb.riken.jp/db/mgi_rdf/MGI:5446656

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Vav1-Lin28b)C3Apla/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vav1-Lin28b)C3Apla

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Sarah H. Beachy, et.al., Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma., Blood, 2012, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/22723554