increased single-positive T cell number_Foxo1<tm1Flv>/Foxo1<tm1Flv>,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0008082I129S6SvEvTacC57BL6DBA2Foxo1tm1FlvFoxo1tm1FlvTgCd4cre1CwiTgCd4cre1CwiFoxo1tm1Flv

increased single-positive T cell number_Foxo1<tm1Flv>/Foxo1<tm1Flv>,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box O1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890077
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxo1<tm1Flv>/Foxo1<tm1Flv>,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Foxo1<tm1Flv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased single-positive T cell number
  http://purl.obolibrary.org/obo/MP_0008082

文献

http://purl.org/net/cito/citesAsAuthority

• Weiming. Ouyang, et.al., An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19285438