decreased single-positive T cell number_Itk<tm1Litt>/Itk<tm1Litt>,Txk<tm1Pls>/Txk<tm1Pls>

http://metadb.riken.jp/0008083I129S4SvJae129S6SvEvTacItktm1LittItktm1LittTxktm1PlsTxktm1PlsItktm1LittTxktm1Pls

decreased single-positive T cell number_Itk<tm1Litt>/Itk<tm1Litt>,Txk<tm1Pls>/Txk<tm1Pls>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• IL2 inducible T cell kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96621
• TXK tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:102960

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itk<tm1Litt>/Itk<tm1Litt>,Txk<tm1Pls>/Txk<tm1Pls>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itk<tm1Litt>|Txk<tm1Pls>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased single-positive T cell number
  http://purl.obolibrary.org/obo/MP_0008083

文献

http://purl.org/net/cito/citesAsAuthority

• E M. Schaeffer, et.al., Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity., Science (New York, N.Y.), 1999, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/10213685